It is a new Night and Museum for Ben Stiller, who is joined by several other stars from the original film, as well as new characters from history - including Amy Adams as famed aviatrix Amelia Earhart, Hank Azaria as villainous Egyptian pharaoh Ka Mun Ra, Christopher Guest as Russian tyrant Ivan the Terrible and Alain Chabat as Napoleon. Owen Wilson is back as cowboy Jedediah, and Robin Williams rides again into history as Teddy Roosevelt.

The centerpiece of the film will be bringing to life the Smithsonian Institution, which houses the worlds largest museum complex with more than 136 million items in its collections, ranging from the plane Amelia Earhart flew on her nonstop solo flight across the Atlantic and Al Capones rap sheet and mug shot to Dorothys ruby red slippers and Archie Bunkers lounge chair.